Conjunctival changes induced by prostaglandin analogues and timolol maleate: a histomorphometric study
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چکیده
منابع مشابه
Conjunctival changes induced by prostaglandin analogues and timolol maleate: a histomorphometric study.
PURPOSE To compare histological changes induced by antiglaucoma medications in the rabbit conjunctiva. METHODS Fifty New Zealand rabbits were divided in 5 groups of 10 animals. The left eyes were treated daily with one drop of bimatoprost 0.03%, travoprost 0.004%, latanoprost 0.005%, timolol maleate 0.5% or artificial tears containing benzalkonium chloride (BAK) for 30 days. The right eyes se...
متن کاملConjunctival changes and inflammatory aspects in rabbits' conjunctivas induced by fixed combinations of prostaglandin analogues and timolol maleate
BACKGROUND The purpose of this research is to compare the histological and immunohistochemical changes induced by fixed combinations of timolol maleate and prostaglandin analogues in the rabbit conjunctiva. Thirty left eyes of rabbits, divided into three groups, were treated for 30 days with the following combinations of drugs: bimatoprost 0.03% + timolol 0.5%, travoprost 0.004% + timolol 0.5% ...
متن کاملOcular reaction to timolol maleate.
A patient prescribed timolol maleate for the control of hypertension developed dryness of the eyes. The symptoms improved on withdrawal of the drug. Vigilance for such adverse reactions must be observed in the use of any beta-adrenoreceptor blocking agent.
متن کاملTopical Prostaglandin Analogues and Conjunctival Inflammation in Uveitic Glaucoma
PURPOSE A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma. METHODS Prospective, single-masked case series of 20 patients with uveitis and secondary raised intraocular pressure. Participants were divided into four groups of five patients dependent on their use of topical medication: (1)...
متن کاملPlasma levels and systemic safety of 0.1% unpreserved timolol maleate gel, 0.5% timolol aqueous solution and 0.5% timolol maleate gel.
PURPOSE To compare systemic absorption of three formulations of timolol eye drops: 0.1% timolol maleate gel, 0.5% timolol aqueous solution, and 0.5% timolol maleate gel. METHODS This was a double cross-over phase I study. Cross-over 1: two weeks of 0.1% timolol gel once daily, followed by a 3-week wash-out period and then two weeks of 0.5% timolol aqueous solution twice a day (group 1) or the...
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ژورنال
عنوان ژورنال: Arquivos Brasileiros de Oftalmologia
سال: 2007
ISSN: 0004-2749
DOI: 10.1590/s0004-27492007000600005